免疫吸着

免疫吸着とは？

免疫吸着は、血流から特定の抗体を選択的に除去するために用いられる高度な治療法である。有害な抗体が重要な役割を果たしている様々な自己免疫疾患や症状の治療に非常に効果的です。

免疫吸着はどのように機能するのか？

The process involves passing the patient’s blood through a special column that contains adsorbers. These adsorbers bind to specific antibodies, removing them from the blood. The purified blood is then returned to the patient’s circulation. This procedure is performed on an outpatient basis and typically lasts several hours.

免疫吸着で治療する疾患

免疫吸着は、以下のような幅広い症状の治療に使用できる：

• Autoimmune Diseases: Such as rheumatoid arthritis, lupus, and multiple sclerosis.
• Neurological Disorders: Such as myasthenia gravis and Guillain-Barré syndrome.
• Dermatological Conditions: Such as pemphigus and bullous pemphigoid.
• Transplant Medicine: Prevention and treatment of organ transplant rejection.
• Long Covid: While initial studies (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511006/) showed no effect, newer studies suggest otherwise: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4911576

免疫吸着の利点

• Targeted Therapy: Selectively removes harmful antibodies without affecting other components of the immune system.
• Minimally Invasive: Performed on an outpatient basis, allowing for minimal disruption to daily life.
• Effective Results: Rapid reduction in antibody levels can lead to significant improvement in symptoms.

長期コビド治療における免疫吸着

ロングコビドにおけるImmunoadsorptionの効果がないことを示した初期の研究にもかかわらず、臨床経験は異なることを物語っている。H.E.L.P. Apheresisほど効果的ではないものの、Immunoadsorptionは、H.E.L.P. Apheresisの成功率が80％であるのに対し、臨床の場では10～30％の成功率を示している。Immunoadsorptionの結果が必ずしも永続的でないのは、その単一の作用機序と迅速適用による負担の大きさに起因している可能性がある。

成功率を向上させるためには、この研究（https://www.medrxiv.org/content/10.1101/2024.06.18.24309100v1）のようなさらなる研究が必要である。新しい吸着剤、併用処理、異なる適用スキームが効果を高める可能性がある。

専門知識

At Apheresis Center, we pride ourselves on offering state-of-the-art immunoadsorption treatments. Our team of experienced professionals is dedicated to providing personalized care tailored to each patient’s specific needs. We use the latest technology and adhere to the highest standards of safety and efficacy.

患者体験

• Consultation: Comprehensive evaluation and consultation to determine the suitability of immunoadsorption for your condition.
• Procedure: Performed in a comfortable and controlled environment by our skilled medical team.
• Follow-Up: Continuous monitoring and follow-up to ensure the best possible outcomes.

当社を選ぶ理由

• Expert Team: Our medical professionals have extensive experience in performing immunoadsorption.
• Cutting-Edge Technology: We utilize the latest equipment and techniques to ensure optimal treatment results.
• Patient-Centered Care: We focus on providing compassionate and individualized care to all our patients.

For more detailed information, you can also read our blog post about different types of Apheresis and which type is suitable for which purpose.